Anomalous Induction of Mycobacteriophages Mediated by Mitomycin C
نویسندگان
چکیده
منابع مشابه
Detecting Lactococcus lactis Prophages by Mitomycin C-Mediated Induction Coupled to Flow Cytometry Analysis
Most analyzed Lactococcus lactis strains are predicted to harbor one or more prophage genomes within their chromosome; however, the true extent of the inducibility and functionality of such prophages cannot easily be deduced from sequence analysis alone. Chemical treatment of lysogenic strains with Mitomycin C is known to cause induction of temperate phages, though it is not always easy to clea...
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These studies examined the effect of dicumarol on xanthine dehydrogenase (XDH), an enzyme recently shown to bioreduce mitomycin C. Dicumarol, which has previously been shown to inhibit xanthine oxidase (XO), inhibited both XDH and XO mediated conversion of xanthine to uric acid but potentiated the metabolism of mitomycin C by XDH and XO. Formation of 2,7-diaminomitosene following mitomycin C bi...
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The interaction of hyperthermia and mitomycin C (MMC) was studied in wild-type Chinese hamster ovary cells and in Chinese hamster ovary cells selected for resistance to MMC. Hyperthermic potentiation of MMC activity was maximal if heating was done simultaneously, or up to 3 h following MMC exposure. Heat enhanced the effect of MMC in both drug-sensitive and -resistant cells. Dose enhancement ra...
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Six of ten bacteriocinogenic strains of Clostridium perfringens were inducible by treating the cultures with mitomycin C. Induction did not occur in the continued presence of mitomycin C but only when excess mitomycin C was removed. Cell death was associated with induction of bacteriocin.
متن کاملThe Induction of Mitotic Recombination by Mitomycin C in Ustilago and Saccharomyces.
EGETATIVE heterozygous diploid strains of Ustilago maydis undergo sponVtaneous mitotic crossing over at low frequency, but this frequency can be increased up to 100-fold if the cells are treated with ultraviolet light (UV) (HOLLIDAY 1961b, 1962a, b, 1964). There is no indication that the induced crossing over differs in mechanism from that which has been described for spontaneous mitotic crossi...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 1969
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.4.4.542-544.1969